Report generated at: 06/13/2021 10:41 PM PDT
Spike variants and mutation combinations / mAb neutralization
Columns explained:
- Author: Internal unique reference identifier
- DOI: DOI
- Source: Location of data within reference
- Date: Date data added to database.
- mAb: mAb name or abbreviation
- Variant: Variants of concern (for example, B.1.1.7, B.1.351, P.1), you can find all mutations here, or combination of spike mutations (for example, S:69del+70del+453F)
- SpikeMutations: SARS-CoV2 spike mutation list
- Control: Variant used in control group
- FoldCmp: Modifier of estimate of fold difference from the control “wildtype” virus: <, >, ~
- Fold: Fold difference from the control “wildtype” virus
- Level: Susceptibility level
- Assay: Default assay is pseudovirus. Assays performed using “authentic” virus are indicated
- Include: Entries containing “Exclude” are not displayed on the web
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Spike variants and mutation combinations / plasma neutralization
Columns explained:
- Author: Internal unique reference identifier
- DOI: DOI
- Source: Location of data within reference
- Date: Date data added to database
- Plasma: CP (convalescent plasma), BNT162b2 (BNT162b2 vaccinated persons), mRNA-1273 (mRNA-1273 vaccinated persons), NVX-CoV2373 (NVX-CoV2373 vaccinated persons). For some CP, author-defined disease severity is provided (e.g., Mild, Hospitalized). For some samples, time since convalescence or vaccination is provided in weeks or months (e.g. 4W, 8M)
- Vaccine: Vaccine name
- Infection: For convalescent plasma samples, the infection is the variant that convalescent patients were infected. It is variant name if is known to be one of VOC(variants of concern) of VOI(variants of interest), otherwise by default it’s “Unknown”.
- Variant: Variants of concern (for example, B.1.1.7, B.1.351, P.1), you can find all mutations here, or combination of spike mutations (for example, S:69del+70del+453F)
- SpikeMutations: SARS-CoV2 spike mutation list
- Control: Variant used in control group
- FoldCmp: Modifier of estimate of fold difference from the control “wildtype” virus: <, >, ~
- Fold: Fold difference from the control “wildtype” virus
- Ineffective: Some samples can’t detect neutralizing activity on experimental testing, control testing, or both.
- Level: Susceptibility level
- Assay: Default assay is pseudovirus. Assays performed using “authentic” virus are indicated
- Count: For some studies, data are presented in aggregate. In this case, the count indicates the number of experiments having the same entries in the Foldcmp and Fold columns
- Include: Entries containing “Exclude” are not displayed on the web
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Spike mutation Invitro selection
Columns explained:
- Author: Internal unique reference identifier
- DOI: DOI
- Source: Location of data within reference
- Date: Date data added to database
- mAb: mAb name or abbreviation
- Position: Spike amino acid position
- AAMutation: amino acid mutation
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Spike mutation Invivo selection
Columns explained:
- Author: Internal unique reference identifier
- DOI: DOI
- Source: Location of data within reference
- Date: Date data added to database
- mAb: mAb name or abbreviation
- Dosage: mAb dosage being used. “Low”, “High”, or actual dosage data(like 700mg)
- Host: Host of in vivo test, Human, Hamster, etc.
- Patient: Patient population. Patient sample ID, “Hospitalized”/“NonHospitalized”
- Sampling: Sampling date. “D”: days, “M”: months
- Infection: For convalescent plasma samples, the infection is the variant that convalescent patients were infected. It is variant name if is known to be one of VOC(variants of concern) of VOI(variants of interest), otherwise by default it’s “Unknown”.
- Position: Spike amino acid position
- AAMutation: amino acid mutation
- TotalPatients: Number of patients in the study
- PatientsWithMut: Number of patients which the samples have the mutation
- Note: Additional information
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